Since their identification over twenty-five years ago, the plethora of cell-penetrating peptides (CPP) and their applications has skyrocketed.These 5 to 30 amino acid in length peptides have the unique property of breaching the cell membrane barrier while carrying cargoes larger than themselves into cells in an intact, functional form.CPPs can be c
One of the best characterized fungal membrane microdomains is the MCC/eisosome.The MCC (membrane compartment of Can1) is an evolutionarily conserved ergosterol-rich plasma membrane domain.It is stabilized on its cytosolic face by the abc material eisosome, a hemitubular protein complex composed of Bin/Amphiphysin/Rvs (BAR) domain-containing Pil1 an
RNase P, an RNA-protein complex, is essential for processing tRNAs.Three of the ten protein subunits of Saccharomyces cerevisiae RNase P (and a related complex, RNase MRP) co-purify with yeast telomerase, another RNA-protein complex.The three telomerase-associated proteins, Pop1, 6 and 7, bind to TLC1, the RNA subunit of telomerase.In a recent stud
Abstract Granulicatella and Abiotrophia are genera of fastidious Gram-positive cocci commensal of the oral, genitourinary, and intestinal flora.We report the first case of infective endocarditis caused by Granulicatella sp.in a kidney transplant recipient.A 67-year-old male kidney transplant recipient was admitted to the hospital lorenametaute.com